Second-line Phenotypic Drug Susceptibility Testing
Multidrug-resistant (MDR) TB is caused by strains of MTB resistant to at least isoniazid and rifampicin; for effective MDR patient management, optimized treatment regimens are required.
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Multidrug-resistant (MDR) TB is caused by strains of MTB resistant to at least isoniazid and rifampicin; for effective MDR patient management, optimized treatment regimens are required.
Critical Concentration for PZA Drugs Recommended for the Treatment of DS- TB
The BACTEC MGIT 960 PZA medium tube contains 7 ml of broth.
BACTEC MGIT 960 SIRE Kit for critical concentrations contains the following drugs in lyophilized form.
The BACTEC MGIT 960 susceptibility testing for Streptomycin (S), Isoniazid (I), Rifampin (R) and Ethambutol (E), called SIRE, is a rapid and qualitative method that uses critical test concentrations of the four drugs.
1. Isolates can be grown on solid or liquid media before being tested in the MGIT DST.