Published on LMS

The Truenat is a rapid molecular diagnostic method based on the Nucleic Acid Amplification Testing (NAAT) principle.

Here we discuss the error classes and actions in Truelab.

Trueprep Error Classes

The Trueprep errors are classified as:

Monitoring of Truenat errors

There are various types of errors that occur with the Truenat machines, which include:

• Coded errors related to the Trueprep AUTO v2 sample prep device
• Coded errors related to the Truelab micro-PCR Analyzer
• Non-coded system errors/failures

Monitoring the Trueprep AUTO v2 errors  

After completion of the set number of nucleic acid extractions (i.e., buffer count 05/ 25/ 50/ 100 completed) the Trueprep AUTO v2 device will prompt the alert on its 2- line LCD screen to “Change the reagent pack” and “Insert Reagent Reset Card & Start” on the screen alternatively. When this happens, the new reagent pack needs to be inserted into the device and the buffer count needs to be reset.

Video : Add and view prescription

Evaluation of stores and stocks under the National TB Elimination Programme (NTEP) is important to ensure an uninterrupted supply of anti-TB drugs to patients and avoid the expiry of drugs.

The evaluation also looks at the optimal performance of the supply chain management and informs the policy if there is any need to address certain critical checkpoints for optimal performance at all levels.

This is facilitated through the Ni-kshay Aushadhi application and the physical stock registers.

Drugs that are part of the shorter Bedaquiline (Bdq)-containing regimen have some typical side effects which need close monitoring of Drug Resistant-TB (DR-TB) patients while providing the treatment.

In adults, the dosage of drugs for a shorter oral Bedaquiline (Bdq) - containing Multi-drug Resistant (MDR)/ Rifampicin-resistant Tuberculosis (RR-TB) regimen, varies according to their weight. 

The table below provides drug dosages for adult patients, according to their weight bands, in a shorter oral Bedaquiline-containing MDR/RR-TB regimen.

Table 1 shows the sequence of using replacement drugs to modify the longer oral multi (M)/extensively drug-resistant TB (XDR-TB) regimen. The physician at the nodal and district DR-TB centres (N/DDR-TBC) should use this table to replace the drugs to modify the regimen.