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The Light Emission Diode Fluorescent Microscopy (LED FM) has the same specificity but increased sensitivity as compared to Ziehl-Neelsen (ZN) microscopy.

 

Reliability of LED FM in comparison with culture.

VERSUS CULTURE

Sensitivity (95% CI)

Specificity (95% CI)

84%

(76 - 89%)

98%

(85 - 97%)

 

 

The LED microscopy was more sensitive compared with ZN microscopy

VERSUS ZN MICROSCOPY

Difference in Sensitivity (95% CI)

Difference in Specificity (95% CI)

+6%

(+0.1 - +13%)

0%

(0 - 0%)

 

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