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Classification of TB cases based on history of Previous TB treatment
Content- New case - A TB patient who has never had treatment for TB or has taken anti-TB drugs for less than one month is considered as a new case.
- Previously treated patients have received 1 month or more of anti-TB drugs in the past. They could be further classified as:
- Recurrent TB case - A TB patient previously declared as successfully treated(cured/treatment completed) and is subsequently found to be microbiologically confirmed TB case is a recurrent TB case.
- Treatment After failure patients are those who have previously been treated for TB and whose treatment failed at the end of their most recent course of treatment.
- Treatment after loss to follow-up A TB patient previously treated for TB for 1 month or more and was declared lost to follow-up in their most recent course of treatment and subsequently found microbiologically confirmed TB case
- Other previously treated patients are those who have previously been treated for TB but whose outcome after their most recent course of treatment is unknown or undocumented.
- Transferred In: A TB patient who is received for treatment in a Tuberculosis Unit, after registered for treatment in another TB unit is considered as a case of transfer in.
- Transferred Out : A patient who has been transferred to another recording and reporting unit and whose treatment outcome is unknown.
Classification of TB on the basis of Drug Resistance
ContentResistant Sensitive Unknown / Sensitive Types of Drug Resistance TB (DR TB) Resistant to Isoniazid (H) Rifampicin (R) Fluroquinolones (FQ) =
Ofloxacin, Levofloxacin,
MoxifloxacinGroup A Drugs =
Bedaquiline/ LinezolidH Mono / Poly Drug Resistance Resistant Sensitive Unknown/ Sensitive Unknown/ Sensitive Rifampicin Resistance (RR) Unknown/ Sensitive Resistant Unknown/ Sensitive Unknown/ Sensitive Multi Drug Resistance TB (MDR TB Resistant Resistant Unknown/ Sensitive Unknown/ Sensitive Pre-Extensive Drug Resistance (Pre -XDR) Resistant Resistant Resistant Unknown/ Sensitive Extensive Drug Resistance (XDR) Resistant
Resistant Resistant Resistant Resources:
Classification of TB on the basis of diagnosis
ContentOn the basis of diagnosis, Tuberculosis (TB) can be classified into 2 main types:
- Microbiologically confirmed TB
- Clinically diagnosed TB
Microbiologically Confirmed TB
- Microbiologically confirmed TB refers to a presumptive TB case from which a biological specimen is positive for acid-fast bacilli/ Mycobacterium tuberculosis on smear microscopy, culture, or on a rapid diagnostic molecular test (such as Cartridge-based Nucleic Acid Amplification Test (CBNAAT)/ Truenat).
- All such diagnosed cases should be notified at the source, regardless of whether TB treatment has started.
Clinically Diagnosed TB
- Clinically diagnosed TB refers to a presumptive TB case that is not microbiologically confirmed but has been diagnosed with active TB by a clinician who has decided to give the patient a full course of anti-TB treatment.
- This definition includes cases diagnosed on the basis of X-ray abnormalities or suggestive histology or extrapulmonary cases without laboratory confirmation.
- Clinically diagnosed cases subsequently found to be microbiologically positive (before or after starting treatment) should be reclassified as microbiologically confirmed.
Resources
- Training Modules (1-4) for Programme Managers and Medical Officers, 2020.
- Definitions and Reporting Framework for Tuberculosis, WHO, 2013.
Assessment
Question Answer 1 Answer 2 Answer 3 Answer 4 Correct answer Correct explanation Page id Part of Pre-test Part of Post-test TB is classified on the basis of diagnosis into which of the following? Microbiologically confirmed TB and clinically diagnosed TB Mono-resistant TB and poly-resistant TB Recurrent cases and previously treated cases None of the above 1 TB can be classified on the basis of diagnosis into 2 main types: Microbiologically confirmed TB and Clinically diagnosed TB.